As cyber threats become more advanced and frequent, endpoint protection is no longer a luxury — it’s a necessity, even for small businesses.
Endpoints (desktops, laptops, mobile devices, and servers) are the front lines of cyberattacks. Ransomware, phishing, and zero-day exploits can start with one click from one employee. That’s why having a reliable endpoint protection platform (EPP) is essential to keeping your business secure.
This guide reviews the top endpoint protection solutions for small businesses in 2025, helping you choose the right tool based on features, ease of use, and price.
What Is Endpoint Protection?
Endpoint protection goes beyond traditional antivirus. It includes:
Real-time threat detection and removal
Behavior-based malware prevention
Ransomware protection
Centralized management and alerts
Data loss prevention (DLP)
Integration with firewalls and email security
A strong EPP ensures that every device connected to your network is secured — without slowing productivity.
1. CrowdStrike Falcon Pro
CrowdStrike is known for delivering enterprise-grade protection to businesses of all sizes via cloud-native architecture.
Best for: Businesses needing advanced threat detection
Key features:
AI-powered threat prevention
Real-time response and remediation
Endpoint detection and response (EDR)
Lightweight agent (no performance lag)
Centralized cloud dashboard
Pricing: From $8.99 per endpoint/month
Bonus: Rated highly for stopping ransomware before execution
Ideal for: Growing businesses looking for next-gen protection.
2. Bitdefender GravityZone Business Security
Bitdefender offers a balanced mix of security, simplicity, and affordability, perfect for small offices and remote teams.
Best for: Small teams with mixed-device environments
Key features:
Malware and ransomware protection
Phishing and web attack blocking
Firewall and device control
Cloud and on-premise management options
Patch management add-on available
Pricing: Starts around $77/year for 3 devices
Bonus: Excellent low-impact performance
Perfect for: Teams that want security without complexity.
3. Sophos Intercept X Essentials
Sophos Intercept X is designed to stop threats before they cause harm, using deep learning and rollback technology.
Best for: SMBs with limited IT resources
Key features:
Anti-exploit and anti-ransomware tools
CryptoGuard rollback for encrypted files
AI-driven threat detection
Remote management through Sophos Central
Email and mobile device integration
Pricing: From $2.50 per user/month
Unique: Root cause analysis for all detected threats
Top pick for: Businesses that can’t afford downtime or data loss.
4. ESET PROTECT Entry
ESET is known for lightweight, high-performance antivirus — now upgraded with robust business protection tools.
Best for: Offices needing fast, resource-light protection
Key features:
Real-time malware and ransomware protection
Device control and firewall
Web and email security
Remote management console
Works well on both Windows and macOS
Pricing: From $239/year for 5 devices
Bonus: Minimal system impact
Great for: Environments with legacy hardware or low IT overhead.
5. Trend Micro Worry-Free Services
True to its name, Trend Micro’s SMB solution helps teams worry less by automating most threat responses.
Best for: Service businesses and remote-first teams
Key features:
Cloud-based EDR
Ransomware and phishing protection
Advanced email threat scanning
USB and file-sharing controls
Microsoft 365 integration
Pricing: From $37.75/year per device
Strength: Simple setup, strong real-time protection
Recommended for: Businesses handling sensitive client information.
6. Microsoft Defender for Business
New in the Microsoft 365 ecosystem, Defender for Business offers enterprise-level endpoint protection tailored to small business needs.
Best for: Microsoft 365 users
Key features:
Threat and vulnerability management
Automated investigation and response (AIR)
Endpoint detection and response (EDR)
Integration with Microsoft Intune and Azure
Works seamlessly across Windows and mobile devices
Pricing: Included in Microsoft 365 Business Premium or $3/user/month standalone
Bonus: Native to the Windows environment
Best for: Businesses already using Microsoft tools.